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The Makati Science High School (Makati Science, formal or MakSci, informal) is a public secondary school located in Kalayaan Avenue, Cembo, Taguig City. The school implemented the K-12 system last 2016 and offers the Science and Technology, Engineering and Mathematics (STEM) Strand for Senior High School. Mr. Felix T. Bunagan, PhD is currently serving as principal of the school since April 2023.

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